Carbon monoxide intoxication leads to acute and chronic neurological deficits, but little is known about the specific noxious mechanisms. 1 H magnetic resonance spectroscopy may allow insight into the pathophysiology of CO poisoning by monitoring neurochemical disturbances, yet only limited information is available to date on the use of this protocol in determining the neurological effects of CO poisoning. To further examine the short-term and long-term effects of CO on the central nervous system, we have studied seven patients with CO (...) poisoning assessed by gray and white matter MRS, magnetic resonance imaging and neuropsychological testing. Five patients suffered from acute high-dose CO intoxication and were in coma for 1–6 days. In these patients, MRI revealed hyperintensities of the white matter and globus pallidus and also showed increased choline and decreased N -acetyl aspartate ratios to creatine, predominantly in the white matter. Lactate peaks were detected in two patients during the early phase of high-dose CO poisoning. Two patients with chronic low-dose CO exposure and without loss of consciousness had normal MRI and MRS scans. On follow-up. five of our seven patients had long-lasting intellectual impairment, including one individual with low-dose CO exposure. The MRS results showed persisting biochemical alterations despite the MRI scan showing normalization of morphological changes. In conclusion, the MRS was normal in patients suffering from chronic low-dose CO exposure; in contrast, patients with high-dose exposure showed abnormal gray and white matter levels of NAA/Cr, Cho/Cr and lactate, as detected by 1 H MRS, suggesting disturbances of neuronal function, membrane metabolism and anaerobic energy metabolism, respectively. Early increases in Cho/Cr and decreases of NAA/Cr may be related to a poor long-term outcome, but confirmation by future studies is needed. (shrink)

\noindent\textbf{Introduction} Online interventions hold great potential for Therapeutic Change Process Research (TCPR), a field that aims to relate in-therapeutic change processes to the outcomes of interventions. Online a client is treated essentially through the language their counsellor uses, therefore the verbal interaction contains many important ingredients that bring about change. TCPR faces two challenges: how to derive meaningful change processes from texts, and secondly, how to assess these complex, varied and multi-layered processes? We advocate the use text mining and multi-level (...) models (MLMs): the former offers tools and methods to discovers patterns in texts; the latter can analyse these change processes as outcomes that vary at multiple levels. \noindent\textbf{Method} We (re-)used the data from \cite{Lamers2015} because it includes outcomes and the complete online intervention for clients with mild depressive symptoms. We used text mining to obtain basic text-variables from e-mails, that we analysed through MLMs. \noindent\textbf{Results} We found that we could relate outcomes of interventions to variables containing text-information. We conclude that we can indeed bridge text mining and MLMs for TCPR as it was possible to relate text-information (obtained through text mining) to multi-levelled TCPR outcomes (using a MLM). \noindent\textbf{Discussion} Text mining can be helpful to obtain change processes, which is also the main challenge for TCPR. We showed how MLMs and text mining can be combined, but our proposition leaves open how to obtain the most relevant textual operationalization of TCPR concepts. That requires interdisciplinary collaboration and discussion. The future does look bright: based on our proof-of-concept study we conclude that MLMs and text mining can indeed advance TCPR. (shrink)

Deep Brain Stimulation (DBS) is a relatively new, experimental treatment for patients suffering from treatment-refractory Obsessive Compulsive Disorder (OCD). The effects of treatment are typically assessed with psychopathological scales that measure the amount of symptoms. However, clinical experience indicates that the effects of DBS are not limited to symptoms only: patients for instance report changes in perception, feeling stronger and more confident, and doing things unreflectively. Our aim is to get a better overview of the whole variety of changes that (...) OCD patients experience during DBS treatment. For that purpose we conducted in-depth, semi-structured interviews with 18 OCD patients. In this paper, we present the results from this qualitative study.We list the changes grouped in four domains: with regard to (a) person, (b) (social) world, (c)characteristics of person-world interactions, and (d) existential stance. We subsequently provide an interpretation of these results. In particular, we suggest that many of these changes can be seen as different expressions of the same process; namely that the experience of anxiety and tension gives way to an increased basic trust and increased reliance on one’s abilities. We then discuss the clinical implications of our findings, especially with regard to properly informing patients of what they can expect from treatment, the usefulness of including CBT in treatment, and the limitations of current measures of treatment success. We end by making several concrete suggestions for further research. (shrink)

Develops a logical analysis of dialogue in which two or more parties attempt to advance their own interests. It includes a classification of the major types of dialogues and a discussion of several important informal fallacies.

The book revives the neutral monism of Mach, James, and Russell and applies the updated view to the problem of redefining physicalism, explaining the origins of sensation, and the problem of deriving extended physical objects and systems from an ontology of events.

A consideration of Mach's elements, his philosophy of neutral monism, and philosophy of physics, especially space and time, much of it based on unpublished writings from the Nachlass and other original sources. The historical connection between Mach and logical positivism is shown to be superficial at best, and Mach's elements are shown to be mind independent natural qualities (world-elements) with dynamic force, not limited to human sensations.

Neutral monism is a position in metaphysics defended by Mach, James, and Russell in the early twentieth century. It holds that minds and physical objects are essentially two different orderings of the same underlying neutral elements of nature. This paper sets out some of the central concepts, theses and the historical background of ideas that inform this doctrine of elements. The discussion begins with the classic neutral monism of Mach, James, and Russell in the first part of the paper, then (...) considers recent neo-Russellian versions in the second half. The chances for a revival of neutral monism are probably slight; its key ideas and starting points lie far from those in contemporary philosophy of mind. A better route might be through the philosophy of science and a deeper understanding of causation. (shrink)

This paper attempts to systematically characterize critical reactions in argumentative discourse, such as objections, critical questions, rebuttals, refutations, counterarguments, and fallacy charges, in order to contribute to the dialogical approach to argumentation. We shall make use of four parameters to characterize distinct types of critical reaction. First, a critical reaction has a focus, for example on the standpoint, or on another part of an argument. Second, critical reactions appeal to some kind of norm, argumentative or other. Third, they each have (...) a particular illocutionary force, which may include that of giving strategic advice to the other. Fourth, a critical reaction occurs at a particular level of dialogue (the ground level or some meta-level). The concepts here developed shall be applied to discussions of critical reactions by Aristotle and by some contemporary authors. (shrink)

Grete Hermann’s essay “Die naturphilosophischen Grundlagen der Quantenmechanik” has received much deserved scholarly attention in recent years. In this paper, I follow the lead of Elise Crull who sees in Hermann’s work the general outlines of a neo-Kantian interpretation of quantum theory. In full support of this view, I focus on Hermann’s central claim that limited spatio-temporal, and even analogically causal, representations of events exist within an overall relational structure of entangled quantum mechanical states that defy any unified spatio-temporal description. (...) In my view, Hermann also advances an important transcendental argument that perspectival spatio-temporal representations of nature have their foundations in general relational networks that are not spatio-temporal. The key point is that the adoption of a perspectival system within the general network induces the representation but only for that context. These ideas are consistent with a perspectival subject–object principle in Kant and also with Weyl’s work on Lie groups and their representations. (shrink)

A look at the dynamical concept of space and space-generating processes to be found in Kant, J.F. Herbart and the mathematician Bernhard Riemann's philosophical writings.

A full appreciation for Ernst Mach's doctrine of the economy of thought must take account of his direct realism about particulars (elements) and his anti-realism about space-time laws as economical constructions. After a review of thought economy, its critics and some contemporary forms, the paper turns to the philosophical roots of Mach's doctrine. Mach claimed that the simplest, most parsimonious theories economized memory and effort by using abstract concepts and laws instead of attending to the details of each individual event (...) or experiment. For Mach, the individual case never truly repeated in all of its uniqueness, nor was all of the individual detail of a physical element adequately captured in abstract laws and schemata, however necessary these were for the pursuit of science. As can be shown from specific passages, some already published, some not, Mach's elements included physical qualia in nature similar to Russell's unsensed sensibilia, which existed even where there were no conscious observers. An argument will be presented to make the case that Mach believed in the mind-independent elements from the 1870s on, while other aspects of his thought evolved over time; I have thus dated the references to reflect this historical progression. I concentrate on Mach's ontology, as it bears on economy of thought, not his epistemology per se, which might well have been restricted to observable elements/sensations. After his own conversion to neutral monism, in the 1920s, Bertrand Russell echoed Mach's call for a 'future science' capable of handling the 'intrinsic character' of qualitative data directly without the excessive abstraction of physics. (shrink)

Extension is probably the most general natural property. Is it a fundamental property? Leibniz claimed the answer was no, and that the structureless intuition of extension concealed more fundamental properties and relations. This paper follows Leibniz's program through Herbart and Riemann to Grassmann and uses Grassmann's algebra of points to build up levels of extensions algebraically. Finally, the connection between extension and measurement is considered.

In many contexts a retraction of commitment isfrowned upon. For instance, it is not appreciated,generally, if one withdraws a promise or denies anearlier statement. Critical discussion, too, caneasily be disrupted by retractions, if these occur toofrequently and at critical points. But on the otherhand, the very goal of critical discussion –resolution of a dispute – involves a retraction,either of doubt, or of some expressed point of view.A person who never retracts, not even under pressureof cogent arguments, would hardly qualify as (...) areasonable discussant. Also, inconsistencies in one'sposition, once they have been pointed out, must bedealt with by some kind of retraction. The problem ofretraction is to find a suitable model of dialoguethat allows retractions where they seem reasonable, oreven required, and rules them out (or puts sanctionsupon them) whenever they would become disruptive of awell-organized process of dialogue.The present paper tries to point to a solution basedon the following principles: (1) Retraction rulesdetermine what retractions are permissible, and (2) ifpermissible what the consequences of retraction are.(3) Retraction rules vary according to the type ofdialogue and (4) according to the type of commitmentretracted. For instance, assertions and mereconcessions need to be distinguished, as well aslight-side and dark-side commitments. (5) To accountfor our contradictory intuitions on the issue ofretractions, one may best resort to a complex type ofdialogue in which different retraction rules hold fordifferent parts.The paper explains, summarizes, and expands upon thediscussion of retraction in Commitment inDialogue by Douglas Walton and the present author(cf. Walton and Krabbe 1995). (shrink)

Section 1 contains a survey of options in constructing a formal system of dialogue rules. The distinction between material and formal systems is discussed (section 1.1). It is stressed that the material systems are, in several senses, formal as well. In section 1.2 variants as to language form (choices of logical constants and logical rules) are pointed out. Section 1.3 is concerned with options as to initial positions and the permissibility of attacks on elementary statements. The problem of ending a (...) dialogue, and of infinite dialogues, is treated in section 1.4. Other options, e.g., as to the number of attacks allowed with respect to each statement, are listed in section 1.5. Section 1.6 explains the concept of a chain of arguments.From section 2 onward four types of dialectic systems are picked out for closer study: D, E, Di and Ei. After a preliminary section on dialogue sequents and winning strategies, the equivalence of derivability in intuitionistic logic and the existence of a winning strategy (for the Proponent) on the strength of Ei is shown by simple inductive proofs. (shrink)

This paper discusses several types of relevance criticism within dialogue. Relevance criticism is a way one could or should criticize one's partner's contribution in a conversation as being deficient in respect of conversational coherence. The first section tries to narrow down the scope of the subject to manageable proportions. Attention is given to the distinction between criticism of alleged fallacies within dialogue and such criticism as pertains to argumentative texts. Within dialogue one may distigguish tenability criticism, connection criticism, and narrow-type (...) relevance criticism. Only the last of these three types of criticism constitutes a charge of fallacy and carries with it a burden of proof. In the second it is observed that a full study of narrow-type relevance criticism would require the construction of complicated, many-layered, dialogue systems. Such a study can, however, be profitably preceded by setting up profiles of dialogue that help us discuss the ins and outs of certain types of move. This is illustrated with an example. (shrink)

Formal dialectic has its roots in ancient dialectic. We can trace this influence in Charles Hamblin’s book on fallacies, in which he introduced his first formal dialectical systems. Earlier, Paul Lorenzen proposed systems of dialogical logic, which were in fact formal dialectical systems avant la lettre, with roles similar to those of the Greek Questioner and Answerer. In order to make a comparison between ancient dialectic and contemporary formal dialectic, I shall formalize part of the Aristotelian procedure for Academic debates. (...) The resulting system will be compared (1) with Van Eemeren and Grootendorst’s system of rules of Critical Discussion (the pragma-dialectical discussion procedure), which must, however, first itself be reconstructed as a formal dialectical system, and (2) with a Hamblin-type system, and (3) a Lorenzen-type system. When drawing comparisons, it will become clear that there is a line to be drawn from Aristotle to formal dialectic and pragma-dialectics, extending to contemporary computational models of argument. (shrink)

We shall investigate the similarities and dissimilarities between old and new dialectic. For the ‘old dialectic’, we base our survey mainly on Aristotle’s Topics and Sophistical Refutations, whereas for the ‘new dialectic’, we turn to contemporary views on dialogical interaction, such as can, for the greater part, be found in Walton’s The New Dialectic. Three issues are taken up: types of dialogue, fallacies, and strategies. Though one should not belittle the differences in scope and outlook that obtain between the old (...) and the new dialectic, the paper will show that in many respects the old dialectic foreshadows the new dialectic. (shrink)

Any well-structured argumentative exchange must be preceded by some preparatory stages. In the pragma-dialectical four-stage model of critical discussion, the clarification of issues and positions is relegated to the confrontation stage and the other preparatory matters are dealt within the opening stage. In the opening stage, the parties involved come to agree to discuss their differences and to do so by an argumentative exchange rather than by, say, a sequence of bids and offers. They should also come to agree on (...) the rules of dialogue, on roles, on logical principles, on types of argument, and on the propositions that can be used as basic premises. All in all, a lot of work needs to be done before the first topical argument can be put forward. Especially the opening stage seems prone to further disagreements and protracted discussions, e.g., about the admissibility of particular kinds of argument or particular basic premises. There is also the problem that a successful opening stage threatens to settle matters beforehand and thus put the argumentation stage out of business. The paper suggests some measures that could alleviate the workload of the opening stage, without making the argumentation stage otiose. (shrink)

Criticism may degenerate into quibbling or nitpicking. How can discussants keep quibblers under control? In the paper we investigate cases in which a battle about words replaces a discussion of the matters that are actually at issue as well as cases in which a battle about minor objections replaces a discussion of the major issues. We survey some lines of discussion dealing with these situations in profiles of dialogue.

This paper explores applications of concepts from argumentation theory to mathematical proofs. Note is taken of the various contexts in which proofs occur and of the various objectives they may serve. Examples of strategic maneuvering are discussed when surveying, in proofs, the four stages of argumentation distinguished by pragma-dialectics. Derailments of strategies (fallacies) are seen to encompass more than logical fallacies and to occur both in alleged proofs that are completely out of bounds and in alleged proofs that are at (...) least mathematical arguments. These considerations lead to a dialectical and rhetorical view of proofs. (shrink)

What if in discussion the critic refuses to recognize an emotionally expressed argument of her interlocutor as an argument, accusing him of having presented no argument at all. In this paper, we shall deal with this reproach, which taken literally amounts to a charge of having committed a fallacy of non-argumentation. As such it is a very strong, if not the ultimate, criticism, which even carries the risk of abandonment of the discussion and can, therefore, not be made without burdening (...) oneself with correspondingly strong obligations. We want to specify the fallacies of non-argumentation and their dialectic, i.e., the proper way to criticize them, the appropriate ways for the arguer to react to such criticism, and the appropriate ways for the critic to follow up on these reactions. Among the types of fallacy of non-argumentation, the emphasis will be on the appeal to popular sentiments. Our aim is to reach, for cases of non-argumentation, a survey of dialectical possibilities. By making the disputants themselves responsible for the place of emotion in their dialogues, we hope to contribute to a further development of the theory of dialectical obligations. (shrink)

Argumentative discussion is successful only if, at the concluding stage, both parties can agree about the result of their enterprise. If they can not, the whole discussion threatens to start all over again. Dialectical ruling should prevent this from happening. The paper investigates whether dialectical rules may enforce a decision one way or the other; either by recognizing some arguments as conclusive or some criticisms as devastating. At the end the pragma-dialectical model appears more successful than even its protagonists have (...) claimed. (shrink)

The situationally disqualifying ad hominem attack is an argumentative move in critical dialogue whereby one participant points out certain features in his adversary's personal situation that are claimed to make it inappropriate for this adversary to take a particular point of view, to argue in a particular way, or to launch certain criticisms. In this paper, we discuss some examples of this way of arguing. Other types of ad hominem argumentation are discussed as well and compared with the situationally disqualifying (...) type. The socalled Houtlosser Dilemma highlights the danger of unconditionally condoning ad hominem arguments. We propose a classification of ad hominem, and a more restrictive use of the term 'circumstantial'. Finally, we discuss whether ad hominem arguments are (always?) to be rejected as fallacious. (shrink)

Aristotle's illustrations of the fallacy of Figure of Speech (or Form of Expression) are none too convincing. They are tied to Aristotle's theory of categories and to peculiarities of Greek grammar that fail to hold appeal for a contemporary readership. Yet, upon closer inspection, Figure of Speech shows many points of contact with views and problems that inhabit 20th-century analytical philosophy. In the paper, some Aristotelian examples will be analyzed to gain a better understanding of this fallacy. The case of (...) the Third Man argument and some modern cases lend plausibility to the claim that Figure of Speech is of more interest as a type of fallacy than has generally been assumed. Finally, a case is made for the view that Figure of Speech, though listed among the fallacies dependent upon language, is not properly classified as a fallacy of ambiguity. More likely, it should be looked upon as a type of non sequitur. This has important consequences for the profile of dialogue associated with this fallacy. (shrink)

Ernst Mach and the Vienna Circle are linked historically, but conceptually the views of Mach do not fit well with logical positivism. My purpose in the present paper is to reconsider 1) Mach’s positive natural philosophy 2) what Mach meant by “anti-metaphysics”, 3) whether Mach really was “anti-metaphysical” in the sense of demanding verification in principle for every term or statement in science, and 4) how Mach’s views on metaphysics differed from those of many Vienna Circle philosophers. I believe a (...) strong case can be made for separating Mach’s realistic version of empiricism from that of the Vienna Circle, but perhaps the “received view” of the Vienna Circle philosophers does not describe their views very well either. (shrink)

This paper makes an independent start with formalizing the rules for the argumentation stage of critical discussions. It does not deal with the well-known code of conduct consisting of ten rules but with the system consisting of fifteen rules on which the code of conduct is based. The rules of this system are scrutinized and problems they raise are discussed. Then a formal dialectical system is defined that reflects most of the contents of these rules. The aim is to elucidate (...) the way the rules work and to show how a formal approach can be useful to achieve this. It is also shown how the present method can be used to study the nature of circular argumentation. While, generally, the formalization follows closely the original rules for the argumentation stage of critical discussions, there will also be proposed some modifications of the original protocol. (shrink)

Inconsistent Commitments and Commitment to Inconsistencies.

This article distinguishes between Machian empiricism and the logical positivism of the Vienna Circle and associated philosophers. Mach's natural philosophy was a first order attempt to reform and reorganize physics, not a second order reconstruction of the "language" of physics. Mach's elements were not sense data but realistic events in the natural world and in minds, and Mach admitted unobserved elements as part of his world view. Mach's critique of metaphysics was far more subtle and concerned the elimination of sensory (...) visual imagery from natural science, leaving only concrete elements and functions, very much an inspiration to the young Einstein and Heisenberg and a useful engine of theory construction in physics. (shrink)

William James' Radical Empiricist essays offer a unique and powerful argument for direct realism about our perceptions of objects. This theory can be completed with some observations by Kant on the intellectual preconditions for a perceptual judgment. Finally James and Kant deliver a powerful blow to the representational theory of perception and knowledge, which applies quite broadly to theories of representation generally.

This paper, for two upcoming volumes, makes what I consider to be the definitive textual case for finally rejecting the phenomenalist interpretation of Ernst Mach's works, and his customary association with the Vienna Circle, in favor of a stronger realistic neutral monist reading connecting him to James, Russell and the American realist movement and today's neutral monism (for example my 2014). I hope that this reading will eventually supplant the previously mistaken view of Mach's work and that his views of (...) science and philosophy of space and time can be revised as well. (shrink)

A look at Mach's work on monocular stereoscopy with relation to Mach Bands and the sensation of space.

Systems of formal dialectics articulate methods of conflict resolution. To this end they provide norms to regulate verbal exchanges between the Proponent of a thesis and an Opponent. These regulated exchanges constitute what are known as formal discussions.One may ask what moves, if any, in formal discusions correspond to arguing for or against the thesis. It is claimed that certain moves of the Proponent's are properly designated as arguing for the thesis, and that certain moves of the Opponent purport to (...) criticize the tenability or the relevance of the reasons advanced. Thus the usefulness of formal dialectic systems as models for reasonable argument is vindicated.It is then proposed to make these systems more realistic by incorporating in them a norm of Creative Reasoning that removes the severe restrictions to which the Proponent's arguing was hitherto subject. As a consequence, a certain type of irrelevant reason is no longer automatically excluded. Therefore, it is proposed to extend the Opponent's rights to exert relevance criticism. The new dialectic systems are shown to be strategically equivalent to the original ones. Finally, it is stressed that the Opponent's criticism should not be designated as arguing against the thesis. The Opponent criticizes, but does not argue. (shrink)

An overview of the problem of constructing extension combinatorially from qualities cum dispositional powers. In the model recommended here, Grassmann's algebra provides the combinatorial structure while Machian elements give the content.

This paper for an upcoming journal volume examines Grete Hermann's Naturphilosophischen Grundlagen der Quantenmechanik (1935) and the relative context, or perspectival, interpretation of standard quantum mechanics found therein. I find an argument for the emergence of limited spatio-temporal and retrocausal stories, from a chosen experimental perspective, within a larger set of entangled systems not subject to a spatio-temporal interpretation. This argument can be read in reverse as giving some of the necessary preconditions of spatio-temporal representations as based upon perspectival relations, (...) carrying on a Kantian transcendental argument on one hand, and on the other hand, looking forward to Weyl's use of symmetry groups, Lie algebras and their representations in quantum mechanics. (shrink)

I examine Mach's influence on American philosophy from 1890-1910, on Carus, James, Peirce, the American Realists and J.B. Stallo. I also consider the question of whether Mach was a pragmatist in the sense of Peirce and James. I conclude that early pragmatism was a method-centric theory whereas Mach's empiricism prized agreement with experience and downplayed the significance of inductive-scientific methods in general as a guide to discovery.

This paper offers a "tu quoque" defense of strong AI, based on the argument that phenomena of self-consciousness and intentionality are nothing but the "negative space" drawn around the concrete phenomena of brain states and causally connected utterances and objects. Any machine that was capable of concretely implementing the positive phenomena would automatically inherit the negative space around these that we call self-consciousness and intention. Because this paper was written for a literary audience, some examples from Greek tragedy, noir fiction, (...) science fiction and Dada are deployed to illustrate the view. (shrink)